Temozolamide

Temozolamide : Uses, Dosage, Side effects, Brands & Price In India (2026 Guide)

What is Temozolamide ?

Temozolomide is a prescription oral chemotherapy medicine used primarily to treat certain types of brain tumors, including glioblastoma and anaplastic astrocytoma. It belongs to a class of medicines called alkylating agents and works by damaging the DNA of cancer cells, which can slow or stop their growth.

👉 Doctors commonly prescribe Temozolomide for:

  • Glioblastoma (GBM)
  • Anaplastic astrocytoma
  • Newly diagnosed brain tumors
  • Brain tumors that have not responded adequately to previous treatment

For newly diagnosed glioblastoma, Temozolomide may be used together with radiation therapy and subsequently as maintenance treatment.

👉Why is Temozolamide Prescribed ?

Temozolomide is commonly used for:

  • Glioblastoma Multiforme (GBM)
  • Anaplastic Astrocytoma
  • Newly diagnosed brain tumors
  • Recurrent or treatment-resistant anaplastic astrocytoma

The exact treatment plan depends on the tumor type, treatment history, overall health, and the oncologist's recommendation.

How Temozolamide Works

Temozolomide is converted in the body into an active compound that damages cancer-cell DNA. This DNA damage interferes with cancer-cell replication and can ultimately cause cancer cells to die. Temozolomide also penetrates the central nervous system, making it particularly useful in the treatment of certain brain tumors.

Results of Temozolamide Treatment:

  • Damages cancer-cell DNA
  • Slows cancer-cell growth
  • Helps control tumor progression
  • Can improve treatment outcomes in eligible brain cancer patients

How to Take Temozolamide

  • Taken as an oral capsule
  • Usually taken once daily according to the prescribed treatment schedule
  • Often taken on an empty stomach with a glass of water
  • Swallow capsules whole
  • Do not crush, chew, or open capsules

Treatment schedules vary according to the cancer being treated. Some regimens involve daily treatment during radiation followed by cyclical treatment, while other regimens use 5 consecutive days of treatment followed by a 23-day break.

⚠️ Important Instructions:

  • Follow your oncologist's exact dosage and schedule.
  • Do not take an extra dose if you miss a dose unless instructed by your doctor.
  • If you vomit after taking Temozolomide, contact your doctor rather than automatically taking another dose.
  • Regular blood tests are important during treatment because Temozolomide can affect blood-cell counts.

Temozolamide Dosage Variants

Temozolamide is commonly available in:

  • Temozolomide 20 mg
  • Temozolomide 100 mg
  • Temozolomide 140 mg
  • Temozolomide 180 mg
  • Temozolomide 250 mg

Your oncologist determines the required dose based on your treatment protocol and individual factors. A prescribed dose may require combining different capsule strengths.

Common Side Effects of Temozolamide

Like all medicines, Temozolamide may cause side effects.

Common Side Effects:

  • Nausea
  • Vomiting
  • Fatigue
  • Headache
  • Constipation
  • Diarrhea
  • Loss of appetite
  • Hair loss
  • Mouth sores
  • Weakness
  • Low blood-cell counts

👉 Always inform your doctor if symptoms worsen.

Precautions Before Starting Temozolamide

Inform your doctor if you have:

  • Liver disease
  • Kidney disease
  • Low blood-cell counts
  • Previous allergic reaction to Temozolomide or dacarbazine
  • Any ongoing medications or supplements

Temozolomide can affect blood-cell production, so your doctor may order regular blood tests before and during treatment.

⚠️ Temozolomide can harm an unborn baby and may affect sperm production. Discuss contraception, pregnancy planning, and breastfeeding with your doctor before starting treatment.

Available Brands

Temotide 250 RPG   Rs.1,049.00 | 210/Cap
Temorel 250 Reliance Rs.2,699.00 | 540/Cap
Temcad 100 Cadila Rs.750.00 | 150/cap
Temcad 20 Cadila Rs.400.00 | 80/Cap
Temoget 250 GLS Rs.1,500.00 | 300/Cap
Temother 250 Therdose Rs.1,450.00 | 290/Cap

Temozolamide Price In India -

The price of Temozolamide in India depends on:

  • Brand
  • Strength
  • Dosage form (tablet, suspension, or injection)
  • Pack size

If You Need More Information about Price You Can Buy From Our Website Supermeds or Contact Us - 84325 25386

Frequently Asked Questions

1. Is Temozolomide chemotherapy?

Yes. Temozolomide is an oral chemotherapy medicine belonging to the alkylating-agent class.

2. What cancer is Temozolomide used for?

Temozolomide is primarily used for certain brain tumors, particularly glioblastoma and anaplastic astrocytoma.

3. Can Temozolomide cure brain cancer?

Temozolomide is an important part of treatment for certain brain tumors, but whether treatment can achieve long-term control depends on the tumor type, stage, molecular characteristics, and individual response.

4. Should Temozolomide be taken with food?

Temozolomide capsules are generally taken on an empty stomach with water, according to the prescribed schedule. Follow your oncologist's instructions.

5. Can I stop Temozolomide if I feel better?

No. Do not stop Temozolomide without consulting your oncologist. Treatment duration and breaks are determined according to your specific treatment protocol.

Reference

 

Medical Disclaimer: This information is for educational purposes only and does not replace advice from a qualified oncologist or other healthcare professional. Temozolomide is a prescription chemotherapy medicine and should be used only under appropriate medical supervision.