Enzalutamide

Enzalutamide : Uses, Dosage, Side effects, Brands & Price In India - 2026 Guide

What is Enzalutamide ?

Enzalutamide is a prescription androgen receptor inhibitor used to treat certain forms of advanced prostate cancer. It is a type of androgen receptor pathway inhibitor (ARPI) that works by blocking the action of male hormones (androgens), such as testosterone, on prostate cancer cells.

Enzalutamide may be used in patients with metastatic or non-metastatic prostate cancer depending on the disease state and treatment plan.

👉Why is Enzalutamide Prescribed ?

Enzalutamide is used for the treatment of certain types of advanced prostate cancer, including:

  • Metastatic castration-resistant prostate cancer (mCRPC)
  • Non-metastatic castration-resistant prostate cancer (nmCRPC)
  • Metastatic hormone-sensitive prostate cancer (mHSPC)

It may be prescribed along with androgen deprivation therapy (ADT) unless surgical castration has already been performed.

👉 The choice of Enzalutamide depends on the stage of prostate cancer, previous treatments, disease progression, and the oncologist's treatment plan.

How Enzalutamide Works

Prostate cancer cells can depend on androgen hormones to grow and survive.

Enzalutamide works by interfering with the androgen receptor signaling pathway. It:

  • Blocks androgen binding to the androgen receptor
  • Prevents androgen receptor activation
  • Reduces movement of the receptor into the cell nucleus
  • Interferes with androgen-receptor-mediated gene signaling

Results of Enzalutamide Treatment:

By suppressing androgen receptor signaling, Enzalutamide can:

  • Slow prostate cancer growth
  • Delay disease progression
  • Help reduce or control PSA levels in responsive patients
  • Improve outcomes in eligible patients

How to Take Enzalutamide

  • Taken orally once daily
  • Can be taken with or without food
  • Take at approximately the same time each day
  • Swallow tablets/capsule whole with water

⚠️ Important Instructions:

  • Take Enzalutamide exactly as prescribed by your oncologist.
  • Do not crush, chew, or alter tablets unless your specific product information allows it.
  • Do not stop treatment without consulting your doctor.
  • Enzalutamide is generally continued until disease progression or unacceptable toxicity, according to the treating physician.

Enzalutamide Dosage Variants

Enzalutamide is available in different strengths, including:

  • Enzalutamide 40 mg
  • Enzalutamide 80 mg
  • Enzalutamide 160 mg

The exact formulation and dosing should follow the prescribed product and your oncologist's instructions.

Side Effects of Enzalutamide

Like all cancer medicines, Enzalutamide may cause side effects.

Common Side Effects:

  • Fatigue
  • Hot flushes
  • Headache
  • Dizziness
  • High blood pressure
  • Muscle or joint pain
  • Decreased appetite
  • Weight loss
  • Weakness

👉 Inform your doctor immediately if side effects become severe or persistent.

Precautions Before Starting Enzalutamide

Inform your doctor if you have:

  • A history of seizures
  • Brain injury or stroke
  • Heart disease
  • High blood pressure
  • Liver disease
  • A history of falls
  • Any ongoing medicines or supplements

Enzalutamide can affect the activity of several liver enzymes and drug transporters and therefore has the potential to interact with other medicines.

Available Brands

Enzamide 160 Intas Rs.4,200.00 | 600/Tab
Glenza 160 Glenmark Rs.3,299.00 | 471/Tab
Enzandro 160 Abbott Rs.3,375.00 | 482/Tab
Samenza 40 Samarth Rs.2,715.00 | 97/Cap
Enzaneal Amneal Rs.2,450.00 | 88/Cap


Enzalutamide Price In India -

The price of Enzalutamide in India depends on:

  • Brand
  • Pack Size
  • Manufacturer
  • Generic or innovator product

Patients can also explore:

  • Patient Assistance Programs (PAP)
  • Generic Enzalutamide options
  • Affordable oncology medicine suppliers

If You Need More Information about Price You Can Buy From Our Website Supermeds or Contact Us - 8432525386

👉 Many patients search online for the lowest Enzalutamide price in India and trusted suppliers offering genuine medicines.

Frequently Asked Questions

1. Is Enzalutamide chemotherapy?

No. Enzalutamide is not traditional chemotherapy. It is a targeted hormonal therapy/androgen receptor inhibitor used in prostate cancer.

2. What is Enzalutamide 160 mg used for?

Enzalutamide 160 mg once daily is commonly used for certain advanced forms of prostate cancer, including metastatic castration-resistant and hormone-sensitive prostate cancer, as well as non-metastatic castration-resistant prostate cancer in appropriate patients.

3. Can Enzalutamide be taken with food?

Yes. Enzalutamide can generally be taken with or without food.

4. Is Enzalutamide given with hormone therapy?

In many patients, Enzalutamide is used together with androgen deprivation therapy (ADT) unless the patient has undergone bilateral orchiectomy.

5. Can I stop Enzalutamide if my PSA decreases?

No. A reduction in PSA does not mean treatment should be stopped. Continue Enzalutamide according to your oncologist's prescription unless they advise a change.

6. What is the difference between Enzalutamide and Abiraterone?

Both are hormonal therapies used in advanced prostate cancer, but they work differently. Enzalutamide directly inhibits androgen receptor signaling, whereas Abiraterone inhibits androgen production through CYP17 inhibition and is administered with corticosteroid therapy according to the treatment regimen.

 

References

 

Medical Disclaimer: This information is for educational purposes only and does not replace advice from a qualified oncologist or other healthcare professional. Enzalutamide is a prescription anti-cancer medicine and should be used only under appropriate medical supervision.