Bortezomib : Uses, Dosage, Side effects, Brands & Price In India - 2026 Guide

What is Bortezomib ?

Bortezomib is a prescription anticancer medicine belonging to the proteasome inhibitor class. It is primarily used in the treatment of multiple myeloma and mantle cell lymphoma, depending on the patient's condition and the applicable treatment regimen.

Bortezomib works by blocking proteasomes, cellular structures that help regulate proteins inside cells. This disruption can lead to cancer-cell death. It is administered by a trained healthcare professional, usually by subcutaneous injection or intravenous injection.

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👉Why is Bortezomib Prescribed ?

Bortezomib is prescribed for certain blood cancers, with the treatment regimen depending on the diagnosis, previous treatment and overall health of the patient.

• Multiple Myeloma
• Mantle Cell Lymphoma
  

Important: Bortezomib is not suitable for every patient with these cancers. The treating hematologist or oncologist determines whether it is appropriate.

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How Bortezomib Works

Bortezomib inhibits the activity of the 26S proteasome, a protein complex that breaks down unwanted or damaged proteins inside cells.

When proteasome activity is blocked:

• Abnormal proteins accumulate inside cells.
• Normal cellular protein regulation is disrupted.
• Cancer-cell survival signals may be affected.
• Cellular stress increases, potentially leading to cancer-cell death.

This mechanism makes Bortezomib useful in certain plasma-cell and lymphoma treatment regimens.

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How to Take Bortezomib

Bortezomib is an injectable medicine and must be administered by a trained healthcare professional.

Depending on the prescribed regimen, it may be administered:-

• Subcutaneously (SC): Injection under the skin.
• Intravenously (IV): Injection into a vein.
  

The dose, frequency and duration depend on the cancer being treated and the combination regimen.

⚠️ Important Instructions:

• Use Bortezomib only under specialist medical supervision.
• Never self-administer the injection.
• Follow the prescribed treatment schedule.
• Tell your doctor about numbness, tingling, burning pain or weakness before and during treatment.
• Attend scheduled blood tests and other monitoring appointments.
• Bortezomib must never be administered intrathecally (into the spinal fluid). This route can be fatal.

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Bortezomib Dosage Variants

• Bortezomib 2 mg Injection
• Bortezomib 2.5 mg injection
• Bortezomib 3.5 mg injection

These are product strengths, not interchangeable dosing recommendations. The required dose is calculated and prescribed by the treating specialist according to the treatment protocol and patient-specific factors.

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Side Effects of Bortezomib

Like other anticancer medicines, Bortezomib may cause side effects. Their severity varies between patients.

Common Side Effects:

• Nausea and vomiting
• Diarrhea or constipation
• Fatigue and weakness
• Reduced appetite
• Low platelet count
• Low white blood cell count
• Anemia
• Peripheral neuropathy, including numbness or tingling
• Dizziness or low blood pressure
• Increased risk of infections
  

👉 Inform your doctor immediately if side effects become severe or persistent.

Precautions Before Starting Bortezomib

Inform your doctor if you have:

• Numbness, tingling or nerve problems
• Liver disease
• Heart disease
• Diabetes
• Low blood pressure or a history of fainting
• An active infection or previous shingles
• Kidney problems
• Any other medical condition

Also inform your doctor about all prescription medicines, OTC medicines, vitamins and herbal supplements, because Bortezomib can interact with other medicines.

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Available Brands

Bortemib 2	Khandelwal Lab	Rs.630.00 / Vial
Borviz 2.5	Intas	Rs.1750.00 / Vial

Bortezomib Price In India -

The price of Bortezomib in India depends on:

• Brand
  
• Pack Size
• Manufacturer
• Generic or innovator product

Patients can also explore:

• Patient Assistance Programs (PAP)
• Generic Bortezomib options
• Affordable oncology medicine suppliers

If You Need More Information about Price You Can Buy From Our Website Supermeds or Contact Us - 8432525386

👉 Many patients search online for the lowest Bortezomib price in India and trusted suppliers offering genuine medicines.

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Frequently Asked Questions

What is Bortezomib used for?

Bortezomib is used in specific treatment regimens for multiple myeloma and mantle cell lymphoma.

What is Bortezomib 3.5 mg injection?

Bortezomib 3.5 mg is one of the available injection strengths. The prescribed dose depends on the treatment regimen and individual patient factors.

How does Bortezomib work?

Bortezomib blocks proteasomes, disrupting protein breakdown inside cells and potentially triggering cancer-cell death.

Is Bortezomib given intravenously or subcutaneously?

It may be given into a vein (IV) or under the skin (SC), depending on the prescribed regimen and product instructions. It must be administered by trained healthcare professionals. It must never be injected into the spinal fluid.

What are the common side effects of Bortezomib?

Common side effects can include fatigue, nausea, diarrhea, low blood counts, infections and peripheral neuropathy. Contact your doctor if symptoms worsen.

Does Bortezomib cause nerve damage?

Yes. Bortezomib can cause peripheral neuropathy, which may present as numbness, tingling, burning pain or weakness. Report these symptoms promptly to your treating team.

What is the price of Bortezomib in India?

The price depends on the brand and strength. Online listings provide indicative prices, but patients should confirm the current price and availability with a licensed pharmacy.

Can Bortezomib be used without a prescription?

No. Bortezomib is a prescription anticancer medicine and should only be used under specialist supervision.

References

References

National Pharmaceutical Pricing Authority (NPPA): Historical listed brand and price information. Read reference